As any kid will tell you, grown-ups like to make things complicated. And they rarely miss a chance to argue about stuff.

Case in point: the COVID-19 vaccination for children ages 5 to 11.

The U.S. Food and Drug Administration has granted emergency use authorization for kid-sized doses of the vaccine made by Pfizer and BioNTech. That paves the way for making it available to elementary-school-age children by the end of the week.

The action had been recommended by a panel of experts who advise the FDA on vaccines. When it comes to adults and older kids, groups like this have almost always said everyone should get vaccinated. But this time was different: Several members made clear that they do not think the vaccination should be given to as many young children as possible, at least right now.

This week, another group of vaccine experts that advises the Centers for Disease Control and Prevention will debate which 5- to 11-year-olds should get vaccinated.

They’re likely to argue — and they’ll definitely make things look complicated.

Why all the drama?

You might be wondering why there’s even a question about whether to vaccinate kids against COVID-19.

The danger of the disease seems clear: At least 94 children ages 5 to 11 have died of COVID-19 since the pandemic began, and 8,300 have become so sick they needed to be hospitalized.

Even some who had only mild symptoms went on to develop MIS-C, a condition in which the immune system goes haywire and starts attacking perfectly healthy parts of the body. By early October, 5,217 kids had come down with MIS-C, including 2,034 between 6 and 11. Between 1% and 2% of them died.

There’s also the possibility they could develop “long COVID.” In Great Britain, about 8% of kids who knew they had a coronavirus infection suffered symptoms that lingered for months. They had fatigue or muscle aches or breathing problems or trouble concentrating in school.

There’s another big reason to consider vaccinating young kids: getting back to normal.

No one loves wearing a mask all day, or having to spend two weeks in quarantine after being exposed to an infected person. If most kids got vaccinated, a lot of pandemic restrictions would probably get tossed out and kids could resume their normal lives.

What’s not to like?

Not everyone sees it this way. Some parents still aren’t ready to get their kids vaccinated, and not all experts are sure that every kid needs to be. Over the entire pandemic, the chance that a kid of any age would die of COVID-19 never rose above one in 2 million (and was usually way lower). That’s four times less than the odds of being struck by lightning in any given year.

Plus, more than half of young kids with coronavirus infections have practically no symptoms at all. The kids that have been least likely to get very sick or die are the ones between 5 and 11. Babies and teenagers were more likely to get sick if they got infected, and more of them died.

Given all that, these skeptics ask, why would you run the risk of getting every young kid jabbed with COVID-19 vaccine — especially if there are safety issues that researchers don’t yet understand?

A scary heart problem

One of the main things the FDA advisors argued about was a rare vaccination side effect that may not even affect kids under 12 after they get this COVID-19 vaccine. The side effect is called myocarditis, and it irritates the heart muscle, causing some swelling and often chest pain.

Myocarditis after an mRNA vaccination is definitely unusual: If you vaccinated 1 million 16- or 17-year-old boys and gave them the adult version of this Pfizer vaccine, about 70 of them would experience some form of the condition. It seems to go away on its own, but if you get it, you’ll probably spend several days in the hospital. When these patients get out, they’ll be advised to quit sports for three to six months just to be sure they’re OK.

The problem is that no one is sure whether myocarditis hurts a child’s heart in any lasting way. Nor do they know whether younger kids who haven’t started puberty could get it in the first place. They are counting on the kid-sized dose to be too small to set off any such reaction.

How will we find out?

This is one of the problems that comes with judging the safety of a new vaccine during a public health emergency. To speed the task of making sure this vaccine works safely in young kids, government experts relied on some of the safety data from previous trials and asked Pfizer to test smaller doses in a few thousand kids in the 5-to-11 age group.

Even if myocarditis occurred as often in little kids as it does in teenagers, you’d need more than 14,000 kids in your test group to have one case of myocarditis. With a test group of less than 3,000 kids, odds are good you won’t see any cases.

But that doesn’t mean they won’t happen — and no one will know until millions of kids start getting vaccinated.

The idea of marching millions of kids into such an uncertain situation is unnerving to some experts. But the government has a system for keeping tabs on reports of possible vaccination side effects. The FDA assured its advisors that if cases of myocarditis start cropping up, they’ll put vaccinations on hold while they figure out whether there’s a connection and let people know what they’ve found.

Do kids already have some protection?

Maybe. Kids in grade school can catch the coronavirus easily. Even if it doesn’t make them sick, their immune systems learn to recognize it so the next time the virus comes calling, their natural defenses can act quickly to shut it down.

A study by researchers at the CDC found that at least 40% of kids are in this category. But since the coronavirus is new, no one is sure how long a child’s immune system will remember it, or how strong the protection will be.

With all this in mind, does it make sense to rush out and vaccinate them all? Some experts don’t think so.

Is it over yet?

A lot of adults have been sure the pandemic was just about over, and, boy, have they been proved wrong. Four separate times, we’ve seen infections and deaths climb, then fall. And every time so far, they’ve gone back up again.

But when considering whether most younger kids need the vaccination, it really matters whether the end is in sight. If the virus just can’t spread as fast because so many people have immunity, maybe most kids don’t need more protection — especially since there may be risks to getting all kids in this age group vaccinated.

On the other hand, if another surge is on the horizon, taking that risk might be a really good way to stop it from happening.

All kids? Or just some?

As the CDC advisors discuss the vaccine on Tuesday, one thing to listen for is whether they think all kids between 5 and 11 should get vaccinated against COVID-19, or whether they think kids in this age group should have the chance to get vaccinated if their parents or guardians think it’s a good idea?

Here too, there are differences of opinion, and good arguments on both sides.

Does the vaccine do more to protect young kids or those around them?

Although most young kids with coronavirus infections don’t get sick themselves, they are good at spreading the virus — and it can be hard to tell that it’s happening because they may seem perfectly fine while they’re doing it. That’s a real problem if they live with or go to school with people who could get very sick if they’re infected.

That includes other kids who have asthma, diabetes or obesity, as well as parents or grandparents who’ve had cancer or chronic heart problems. The young children in these situations probably should get vaccinated to cut off the chain of transmission before it reaches those who are vulnerable.

The kids with these higher-risk health conditions ought to get vaccinated too to protect themselves, experts say.

Why does anyone get vaccinated?

Mostly, to protect ourselves. But also to protect each other.

The more people who get vaccinated, the more protection there is for the most vulnerable among us. For a lot of people, it would be worth running a small risk of a vaccination side effect — even one like myocarditis — to help protect a classmate or grandparent.

One thing is clear: Kids should be protected

Here’s the last thing worth saying about grown-ups: They love their little kids, and — no surprise here — will defend them fiercely against any harm. That’s why some adults who’ve been vaccinated against COVID-19 themselves might need more information before they’d get their children vaccinated, while others take their kids straight to the pediatrician for their first dose.

It’s complicated.





Source link

https://wakelet.com/wake/zVQtGbPfoqrkaj89OcaLW
https://wakelet.com/wake/2XDXpSbwneG9KahGu_H0a
https://wakelet.com/wake/5IBLmGA-NUIhl4THEIm4q