MEXICO CITY — The U.S. government offered $5 million rewards Friday for information leading to the capture of four Mexican drug lords.

Those subject to the $5 million bounty included Aureliano Guzman-Loera, the brother of imprisoned capo Joaquin “El Chapo” Guzman.

Guzman-Loera and three brothers from the Salgueiro-Nevarez family were indicted in the United States of conspiring to traffic marijuana, cocaine, methamphetamine, and fentanyl.

The State Department said the four operate in the northern Mexico states of Sinaloa and Chihuahua, and are leaders of the Sinaloa cartel.

Fentanyl, a synthetic opioid, was responsible for about 61,000 overdose deaths in the United States between March 2020 and 2021.